Shim-Mo Hayashi Selected Research

Body Weight (Weight, Body)

1/2021	Dietary administration of β-ionone epoxide to Sprague-Dawley rats for 90 days.
1/2020	Dietary administration of β-caryophyllene and its epoxide to Sprague-Dawley rats for 90 days.
12/2018	Chronic dietary toxicity and carcinogenicity studies of dammar resin in F344 rats.
10/2018	Absence of adverse effects following administration of piperine in the diet of Sprague-Dawley rats for 90 days.
10/2018	Absence of renal adverse effects from β-myrcene dietary administration in OECD guideline-compliant subchronic toxicity study.
1/2018	Spironolactone in Combination with α-glycosyl Isoquercitrin Prevents Steatosis-related Early Hepatocarcinogenesis in Rats through the Observed NADPH Oxidase Modulation.
4/2017	Anti-inflammatory effects of the selective phosphodiesterase 3 inhibitor, cilostazol, and antioxidants, enzymatically-modified isoquercitrin and α-lipoic acid, reduce dextran sulphate sodium-induced colorectal mucosal injury in mice.
1/2013	Evaluation of 90-day oral rat toxicity studies on the food additive, gum ghatti.

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Shim-Mo Hayashi Research Topics

Disease

8	Neoplasms (Cancer) 01/2024 - 04/2007
8	Body Weight (Weight, Body) 01/2021 - 01/2013
4	Colitis 10/2017 - 02/2017
4	Inflammation (Inflammations) 09/2017 - 04/2011
3	Colorectal Neoplasms (Colorectal Cancer) 10/2021 - 02/2017
3	Chromosome Aberrations (Chromosome Abnormalities) 08/2018 - 01/2017
2	Hypothyroidism 07/2019 - 01/2019
2	Colonic Neoplasms (Colon Cancer) 09/2017 - 02/2017
2	Hyperplasia 08/2010 - 04/2007
1	Neuroblastoma 11/2023
1	Erythema 01/2022
1	Hypertrophy 01/2020
1	Hyperlipidemias (Hyperlipidemia) 01/2018
1	Insulin Resistance 01/2018
1	Liver Diseases (Liver Disease) 01/2018
1	Obesity 01/2018
1	Non-alcoholic Fatty Liver Disease 01/2018
1	Necrosis 04/2017
1	Wounds and Injuries (Trauma) 04/2017
1	Lymphoma (Lymphomas) 11/2016
1	Ulcer 01/2013
1	Basophil Adenoma 04/2007

Drug/Important Bio-Agent (IBA)

9	isoquercitrinIBA 01/2024 - 04/2011
7	AntioxidantsIBA 01/2024 - 02/2017
4	SodiumIBA 10/2017 - 08/2010
3	Proteins (Proteins, Gene)FDA Link 07/2019 - 09/2017
3	Thioctic Acid (Lipoic Acid)IBA 07/2019 - 02/2017
3	Dextrans (Dextran)FDA Link 10/2017 - 02/2017
3	CytokinesIBA 09/2017 - 04/2011
2	Epoxy Compounds (Epoxides)IBA 01/2021 - 01/2020
2	Protein Kinases (Protein Kinase)IBA 10/2017 - 09/2017
2	Phosphotransferases (Kinase)IBA 10/2017 - 09/2017
2	AzoxymethaneIBA 09/2017 - 02/2017
2	Drinking WaterIBA 09/2017 - 04/2017
2	Interleukin-6 (Interleukin 6)IBA 09/2017 - 04/2011
2	Cilostazol (Pletal)FDA LinkGeneric 04/2017 - 02/2017
1	Taurine FDA Link 11/2023
1	Food Additives (Food Additive)IBA 05/2023
1	FlavonoidsIBA 05/2023
1	Anti-Infective Agents (Microbicides)IBA 01/2022
1	formamideIBA 01/2022
1	Metronidazole (Metric)FDA LinkGeneric 01/2022
1	CurcuminIBA 10/2021
1	Fluorouracil (Carac)FDA LinkGeneric 10/2021
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 10/2021
1	Therapeutic UsesIBA 10/2021
1	Hypoglycemic Agents (Hypoglycemics)IBA 10/2021
1	Irinotecan (Camptosar)FDA LinkGeneric 10/2021
1	Norisoprenoids (Irones)IBA 01/2021
1	caryophylleneIBA 01/2020
1	Hemoglobins (Hemoglobin)IBA 12/2018
1	CholesterolIBA 10/2018
1	myrceneIBA 10/2018
1	genipinIBA 08/2018
1	Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA 01/2018
1	NADPH Oxidases (NAD(P)H oxidase)IBA 01/2018
1	Blood Glucose (Blood Sugar)IBA 01/2018
1	nasIBA 01/2018
1	Spironolactone (Aldactone)FDA LinkGeneric 01/2018
1	LipidsIBA 01/2018
1	DiureticsIBA 01/2018
1	Dextran SulfateIBA 09/2017
1	ChemokinesIBA 04/2017
1	InterleukinsIBA 04/2017
1	Anthocyanins (Anthocyanin)IBA 02/2017
1	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 02/2017
1	Magnesium Sulfate (Sulfate, Magnesium)FDA LinkGeneric 01/2017
1	stearic acid (magnesium stearate)FDA LinkGeneric 01/2017
1	perillaldehydeIBA 11/2016
1	Hypoxanthine Phosphoribosyltransferase (Hypoxanthine Guanine Phosphoribosyltransferase)IBA 11/2016
1	Piperonyl Butoxide FDA Link 08/2014
1	TensinsIBA 08/2014
1	Transforming Growth Factors (Transforming Growth Factor)IBA 08/2014
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 08/2014
1	gum ghattiIBA 01/2013
1	EnzymesIBA 04/2011
1	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 04/2011
1	nisin AIBA 08/2010
1	PotassiumIBA 08/2010
1	ChlorineIBA 08/2010
1	QuercetinIBA 04/2007

Therapy/Procedure

1	Drug Therapy (Chemotherapy) 10/2021
1	Intraperitoneal Injections 09/2017